1 2 4 trichlorobenzene structure

Future versions of this site may rely on Avoid areas near facilities that manufacture and use trichlorobenzenes and other chlorinated substances or hazardous waste sites that contain these substances. Process wastes from the production of certain chlorinated aliphatic hydrocarbons by free radical catalyzed processes, as defined. Soc., 1949, 71, 7, 2575-2576, https://doi.org/10.1021/ja01175a094 Structure, properties, spectra, suppliers and links for: 1,1'-[(4-{2-[4-(Dimethyliminio)-2,5-cyclohexadien-1-ylidene]ethylidene}-4H-pyran-2,6-diyl)di-2,1. Data from NIST Standard Reference Database 69: The National Institute of Standards and Technology (NIST) Follow the links above to find out more about the data Moreover, the free concentration Get all suppliers and price by the below link: Home | Even though the forms have the same molecular weight and molecular formulae, they are structurally different by the positions of the chlorine atoms attached to the benzene ring. The isomers may also have different chemical and toxicological properties.[2][3]. Understanding Solidification of Polythiophene Thin Films during Spin-Coating: Effects of Spin-Coating Time and Processing Additives. H tue of their chemical structure and amount present, form soluble metal complexes which are not removed by subsequent metals control techniques . Usually, benzene, chlorobenzene, 1,2,4-trichlorobenzene, tetrachloromethane, and carbon disulfide were used as solvent. United States Environmental Protection Agency. Imaging flow cytometry makes it possible. 1,2,4-Trichlorobenzene for synthesis. How can trichlorobenzenes affect my health? LLK - Sharon G. Lias, Rhoda D. Levin, and Sherif A. Kafafi, Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, Data compiled by: Tanya L. Myers, Russell G. Tonkyn, Ashley M. Oeck, Tyler O. Danby, John S. Loring, Matthew S. Taubman, Stephen W. Sharpe, Jerome C. Birnbaum, and Timothy J. Johnson, Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director, Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, UV/Visible spectrum, References, Notes. 1,2,4-Trichlorobenzene | C6H3Cl3 - PubChem Apologies, we are having some trouble retrieving data from our servers. All information these cookies collect is aggregated and therefore anonymous. Cosolvents are often needed to dissolve these chemicals in cell culture medium. However, NIST makes no warranties to that effect, and NIST Am. (5) 1,2,4-Trichlorobenzene occurs as a colorless liquid that is insoluble in water. Thermodynam., 1982, 14, 303-308. . : Washington, D. C., 1955. United States Environmental Protection Agency, Some of the following links exit EPA's site, Program and regulatory information about this substance, including links to EPA applications/systems, statues/regulations, or other sources that track or regulate this substance, Standards for Owners and Operators of Hazardous Waste Treatment, Storage, and Disposal Facilities, Guidelines Establishing Test Procedures for the Analysis of Pollutants, Water Quality Guidance for the Great Lakes System, Criteria for Municipal Solid Waste Landfills, Management of Specific Hazardous Wastes and Specific Types of Hazardous Waste Management Facilities, Interim Standards for Owners & Operators of Hazardous Waste Treatment Storage & Disposal Facilities. Molar excess volumes and excess heat capacities of (1,2,4-trichlorobenzene + an alkane), Trichlorobenzenes have primarily been used as solvents and chemical intermediates to produce other compounds. Some documentation and label information may refer to the legacy brand. There are no studies of cancer in people exposed to trichlorobenzenes. jcamp-dx.js and Medium. Data compiled by: Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein, Go To: Top, Gas phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, Data compiled as indicated in comments: Determination of the liquid vapour pressure of low-volatility compounds from the Kovts retention index, The effects of exposure to any hazardous substance depend on the dose, the duration, how you are exposed, personal traits and habits, and whether other chemicals are present. Chemsrc provides 1,2,4-Trichlorobenzene(CAS#:120-82-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Soc., 1952, 74, 3890-1. For more information about the substance, you may click one of the links below to take you to the relevant section: Below are the EPA applications/systems, statutes/regulations, or other sources that track or regulate this substance. Your contract pricing may differ. Price (EUR) Price: 98,60. Order 1,2,4-Trichlorobenzene as Catalog No. intended to imply recommendation or endorsement by the National Standard enthalpies of formation and enthlpies of isomerization of trichlorobenzenes, The reaction is as follows: HeH + He + H +. Database and to verify that the data contained therein have Jondorf, W.R.; Williams, R.T., Based on data from 279. [all data], Wilhelm, Inglese, et al., 1982 View image of digitized The isomers differ slightly from each other in their chemical structure. Molecular Weight 181.45. Institute of Standards and Technology, nor is it intended to imply H410: Very toxic to aquatic life with long lasting effects. The preparation method of any one of Claims 1 to 9, wherein, the first solvent is selected from one or a mixture of two or more of 1,2,4-trichlorobenzene, o-dichlorobenzene, chlorobenzene, anisole, toluene, nitrobenzene, isopropyl alcohol, Contents 1 Production and uses 2 Safety 3 See also 4 References Production and uses [ edit] HeH + has bond order 1.. It is a derivative of benzene with three chloride substituents. Please see the following for information about 2-Bromo-1,3,4-trichlorobenzene We do not know whether children would be more susceptible to the effects of trichlorobenzenes than adults. Use or mention of technologies or programs in this web site is not CHCl. Email: Contact CDC-INFO. Am. Chem. These cookies perform functions like remembering presentation options or choices and, in some cases, delivery of web content that based on self-identified area of interests. Aside from its use as a solvent, this compound is a useful precursor to dye and pesticides. displays seen below. 1,2-Dichlorobenzene, or orthodichlorobenzene (ODCB), is an organic compound with the formula C 6 H 4 Cl 2.This colourless liquid is poorly soluble in water but miscible with most organic solvents. shall not be liable for any damage that may result from 1,2,4-Trichlorobenzene is an organochlorine compound, one of three isomers of trichlorobenzene. . Toggle navigation. J., 2001, 7, 16, 3511-3516, https://doi.org/10.1002/1521-3765(20010817)7:16<3511::AID-CHEM3511>3.0.CO;2-U The Preparation of 2,3,5-Trichlorophenoxyacetic acid (2,4,5-T), Biochem. You will need Adobe Reader to view some of the files on this page. Your institution may already be a subscriber. NIST Standard Reference The Food and Drug Administration (FDA) has determined that the concentration of 1,2,4-trichlorobenzene in bottled drinking water should not exceed 0.07 mg/L. This may be a synopsis of the full weight-of-evidence narrative. The chemical formula for 1,2,4-trichlorobenzene is C 6 H 3 Cl 3, and its molecular weight is 181.46 g/mol. on behalf of the United States of America. [all data], Weast and Grasselli, 1989 and Informatics, NIST / TRC Web Thermo Tables, professional edition (thermophysical and thermochemical data). [all data], Sears and Hopke, 1949 (e.g., INSTITUTE OF ENERGY PROBLEMS OF CHEMICAL PHYSICS, RAS, Constant pressure heat capacity of liquid, Temperature dependence parameter for Henry's Law constant, Enthalpy of combustion of liquid at standard conditions, Enthalpy of formation of gas at standard conditions, Enthalpy of formation of liquid at standard conditions, Free energy of reaction at standard conditions, Enthalpy of reaction at standard conditions, Enthalpy of vaporization at standard conditions. [all data], Jondorf and Williams, 1958 Converge, Intensify and Evolve. It is a derivative of benzene with three chloride substituents. If you have questions or concerns, please contact your community or state health or environmental quality department or: For more information, contact: Yan, H.; Gu, J.; An, X.; Hu, R., CAS 120-82-1, chemical formula CH-1,2,4- (Cl). H302: Harmful if swallowed. There is virtually no information regarding health effects of trichlorobenzenes in humans. CAS 120-82-1. Transl. 1,2,4-Trichlorobenzene is a highly chlorinated aromatic solvent. A method for forming a multilayer meltblown composite, consisting of: meltblowing a first material to form a first meltblown layer, wherein the first material comprises one or more resins having an Ultimate Elongation (UE) of from about 50% to about 250%; meltblowing a second material to form a second meltblown layer, wherein the second material comprises one or more . This fact sheet is one in a series of summaries about hazardous substances and their health effects. P = vapor pressure (bar) CAS 120-82-1, chemical formula CH-1,2,4- (Cl). H302: Harmful if swallowed. These clinics specialize in recognizing, evaluating, and treating illnesses resulting from exposure to hazardous substances. Structure comprising metallized film and ethylene copolymer AT425217T (de) * 2005-05-12: 2009-03-15: Dow Global Technologies Inc: . Rohc, Vladislav; Ruzicka, Vlastimil; Ruzicka, Kvetoslav; Aim, Karel, See EPAs PDF page to learn more. Eng. Compound E is 4-Bromo 1-chloro 2-methyl benzene. 15, Am. endstream endobj 26 0 obj <>stream Data, 1960, 5, 2, 196-200, https://doi.org/10.1021/je60006a019 . It is useful as a high-temperature solvent, e.g. Pays-Bas, 1932, 51, 98-113. Chim. Journals | uses its best efforts to deliver a high quality copy of the Trichlorobenzenes are volatile and preferentially enter the air when released to the environment. We take your privacy seriously. with the development of data collections included in This table shows how each list refers to the substance. Primary and secondary antibodies, blockers and custom services. What Generation is Your Sterility Testing Pump? https://en.wikipedia.org/w/index.php?title=Trichlorobenzene&oldid=1074841239, Creative Commons Attribution-ShareAlike License 3.0, This page was last edited on 2 March 2022, at 13:41. Animal studies have shown that 1,2,4-trichlorobenzene affects the liver and kidney, and is possibly a teratogen. All Rights Reserved. [all data], Ruscic, Klasinc, et al., 1981 Agency for Toxic Substance and Disease Registration. Your fast track through regulatory challenges.. Functional excipients to enhance bioavailability. Long term administration of 1,2,4-trichlorobenzene to rats did not affect their capacity to have normal offspring. Ruscic, B.; Klasinc, L.; Wolf, A.; Knop, J.V., Reference Concentration for Inhalation Exposure (RfC) (PDF) (14 pp, 118 K) 120-82-1. The product quantity has been adjusted. . 4770 Buford Highway 1,2,4-trichlorobenzene EC Number: 204-428- EC Name: 1,2,4-trichlorobenzene CAS Number: 120-82-1 Molecular formula: C6H3Cl3 IUPAC Name: 1,2,4-trichlorobenzene. (1) The vapor pressure for 1,2,4-trichlorobenzene is 0.29 mm Hg at 25 C, and its log octanol/water partition (1) The vapor pressure for 1,2,4-trichlorobenzene . [1] Trichlorobenzenes are man-made chemical compounds that occur in three different forms. gas phase; Acid: 1,2,4-trichlorobenzene. Our portfolio of innovative products, services and solutions. Depending on the conditions and additives (e.g., sulfur), it can be the main product from the chlorination of benzene. Trichlorobenzenes have been used as solvents. 1,2,4-Trichlorobenzene is an organochlorine compound, one of three isomers of trichlorobenzene. These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. D0-(]PlAm*R5&{b>#7b]'Ddm\Bj. The electronic configuration of HeH + is ( 1 s) 2. Greater control & increased flexibility for both small & large molecule development & manufacturing processes. If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance. CRC Handbook of Data on Organic Compounds, 2nd Editon, Weast,R.C and Grasselli, J.G., ed(s)., CRC Press, Inc., Boca Raton, FL, 1989, 1. binary mixtures and chemical reactions, SRSD 2 Web Thermo Tables (WTT), "lite" edition, SRSD 3 Web Thermo Tables (WTT), professional edition, SRD 156 Clathrate Hydrate Physical Property Database, SOLUTION (10% IN CCl4 FOR 3800-1300, 10% IN CS2 FOR 1300-650, AND 10% CCl4 FOR 650-250 CM, Tanya L. Myers, Russell G. Tonkyn, Ashley M. Oeck, Tyler O. Danby, John S. Loring, Matthew S. Taubman, Stephen W. Sharpe, Jerome C. Birnbaum, and Timothy J. Johnson, liquid; Bruker Tensor 27 FTIR; 0.4821395 cm, NIST Mass Spectrometry Data Center, William E. Wallace, director, Modified by NIST for use in this application, Victor Talrose, Alexander N. Yermakov, Alexy A. Usov, Antonina A. Goncharova, Axlexander N. Leskin, Natalia A. Messineva, Natalia V. Trusova, Margarita V. Efimkina, https://doi.org/10.1016/0021-9673(94)80602-0, https://doi.org/10.1016/S0378-3812(99)00003-5, https://doi.org/10.1002/1521-3765(20010817)7:16<3511::AID-CHEM3511>3.0.CO;2-U. Here, we systematically characterize th Chem. Standard Reference Data Act. Maintain clean baselines and improve chromatography run reproducibility with efficient filtration. Eng. "hFzhkids={S:'.[6Sb:)KUQrFOsaNGfOD3!O-9CqKlT@ HQAW Ks-vWT>NyOKV"}=^8&,%+ It is a colorless liquid used as a solvent for a variety of compounds and materials. This ToxFAQsTM information is taken from the 2014 Toxicological Profile for Trichlorobenzenes produced by the Agency for Toxic Substances and Disease Registry, Public Health Service, U.S. Department of Health and Human Services in Atlanta, GA. However, based on results from studies in animals, it is reasonable to predict that humans exposed to high amounts of trichlorobenzenes may develop liver problems. The product He + H + is stable because in this both the electrons are close to nucleus of hydrogen and helium cation. [all data], van de Lande, 1932 * For the most part, studies in animals given trichlorobenzenes during pregnancy have not found adverse effects in the pups at birth or during the growing period. Petit, J.C.; TerMinassian, L., Fast, safe transfer of plates to isolator. On this Wikipedia the language links are at the top of the page across from the article title. The EPA has determined that exposure to 1,2,4-trichlorobenzene or 1,3,5-trichlorobenzene in drinking water at concentrations up to 0.1 and 0.6 milligrams per liter (mg/L), respectively, for 1 or 10 days is not expected to cause any adverse effects in a child. CAS 120-82-1, chemical formula CH-1,2,4-(Cl). P264: Wash skin thoroughly after handling. The . Volatilization from moist soil surfaces may be an important fate process based upon an estimated Henry's Law . Colorless liquid or crystalline solid (below 63F) with an aromatic odor. The isomers may also have different chemical and . The LD50 (oral, rats) is 756mg/kg. The standard enthalpies of formation of mono-1,2,4- and 1,3,5-tri-, and 1,2,3,4- and 1,2,3,5-tetrachlorobenzenes, Recently, polymerization of structure 102 carried out in 1,2-dichlorobenzene at 25 . Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. Stull, Daniel R., 2021 by the U.S. Secretary of Commerce 1,2,3-Trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, but 1,2,4-trichlorobenzene is a colorless oil. InChI=1S/C6H3Cl3/c7-4-1-2-5(8)6(9)3-4/h1-3H, National Institute of Standards and Knowledgebase & FAQs; Advanced Products; Applications & Protocols Life Science Research Solutions, Products, and Resources Chromatography and Mass Spectrometry . Your institution may already be a subscriber. If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. . J. Chem. Standard Reference Data Act. Technology, Office of Data Polymeric Microspheres and Magnetic Beads, Novabiochem Peptide and DNA Synthesis Reagents, Analytics and Sample Preparation Services, BioReliance Cell and Gene Therapy Testing Services, Calibration, Verification and Suitability Testing, Process Solutions: Portfolio Announcements, Organic Synthesis Building Blocks and Reagents for Pharma. Determination of the standard enthalpies of formation of polychlorobenzenes. Select a region with no data or It is virtually the exclusive product from the chlorination of 1,4-dichlorobenzene. In addition to the Thermodynamics Research Center It is a derivative of benzene, consisting of two adjacent chlorine atoms.. 1,2,3-Trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, but 1,2,4-trichlorobenzene is a colorless oil. This Website requires your browser to be JavaScript enabled. Data from NIST Standard Reference Database 69: The National Institute of Standards and Technology (NIST) All rights reserved. Res. Photoelectron spectra of and Ab initio calculations on chlorobenzenes. such sites. Workers who manufacture or use trichlorobenzenes can be exposed by inhalation and dermal contact with these substances. It is unlikely that the general public will be exposed to high amounts of trichlorobenzenes. Measurements of (dV/dT)p, (dV/dP)T, and (dH/dT)p by flux calorimetry, endstream endobj 27 0 obj <>stream Reference Concentration for Inhalation Exposure (RfC) (PDF) (14 pp, 118 K) Not assessed under the IRIS Program. 1,2,4-Trichlorobenzene, Last Updated Date : Huaxue Xuebao, 1987, 45, 1184. J. [ 1] Application 1,2,4-Trichlorobenzene may be used as a solvent to prepare: dimethylketene -lactone dimer from tetramethyl-1,3-cyclobutanedione [ 2] ; Coefficents calculated by NIST from author's data. How can families reduce their risk for exposure to trichlorobenzenes? This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. uses its best efforts to deliver a high quality copy of the and chemical property data is available from the Chamblee, GA 30341-3717 AC - William E. Acree, Jr., James S. Chickos NOAEL : 1.48 x 10 1. mg/kg-day. 23(11) , 1806-14, (2010). NOAA: CAMEO Chemicals - Platonov, V.A. MSDS/SDS Database Search | Physical description. 1,2,3-Trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, while 1,2,4 trichlorobenzene is a colorless liquid. J. Phys. [all data], Rohc, Ruzicka, et al., 1998 1,2,4-Trichlorobenzene for synthesis. Trichlorobenzenes have been detected in groundwater, drinking water, and surface water (rivers and lakes). Promotional price valid on web orders only. Trichlorobenzenes have been identified in a variety of food items including vegetables, milk, eggs/meat, and oils produced from various nuts and seeds. The interactive spectrum display requires a browser with JavaScript and Organic residuals, excluding spent carbon adsorbent, from the spent chlorine gas and hydrochloric acid recovery processes associated with the production of alpha- (or methyl-) chlorinated toluenes, ring-chlorinated toluenes, benzoyl chlorides, and compounds with mixtures of these functional groups. Chemical Structure for 1,2,4-Trichlorobenzene. H315: Causes skin irritation. Tunnel Dmagntiseurs Plans d'expansion futurs du march, demande par rgions jusqu'en 2030. SRD 103b Thermo Data Engine (TDE) for pure compounds, The Action of Sodium Methylate on SOme Derivatives of m-Dichlorobenzene, Here, the parent ring is styrene a benzene ring is attached to the vinyl unsaturated protons, and the chloro group is present . 2023 Merck KGaA, Darmstadt, Germany and/or its affiliates. It is a colorless liquid used as a solvent for a variety of compounds and materials. Avoiding high consumption of root crops and fish living in trichlorobenzene-contaminated environments will reduce the risk of exposure. J., 1958, 69, 181. You will be subject to the destination website's privacy policy when you follow the link. errors or omissions in the Database. Shanghai Jizhi Biochemical Technology Co., Ltd, 1,2,4-Trichlorobenzene suppliers in China, 5-(4-Chlorophenoxy)-1,2,4-trichlorobenzene, 5-((4-Chlorophenyl)sulfinyl)-1,2,4-trichlorobenzene, 1,2,4-tris(methylthio)-3,5,6-trichlorobenzene. 2,3,5-Trichlorobenzene-1,4-diol | C6H3Cl3O2 - PubChem compound Summary 2,3,5-Trichlorobenzene-1,4-diol Cite Download Contents 1 Structures 2 Names and Identifiers 3 Chemical and Physical Properties 4 Spectral Information 5 Related Records 6 Chemical Vendors 7 Pharmacology and Biochemistry 8 Literature 9 Patents 10 Taxonomy 11 Classification Ind. [all data], Rohc, Ruzicka, et al., 1999 Wilhelm, E.; Lainez, A.; Roux, A.H.; Grolier, J.-P.E., The following components were used in generating the plot: Additonal code used was developed at NIST: Good cell culture practices start with proven products like Stericup and Millex filters. A dermal exposure study in mice was found inadequate for drawing conclusions as to carcinogenicity in humans. III. Cookies used to make website functionality more relevant to you. The presence of trichlorobenzenes in your body does not necessarily mean that you will suffer adverse health effects. H410: Very toxic to aquatic life with long lasting effects. Select search scope, currently: articles+ all catalog, articles, website, & more in one search; catalog books, media & more in the Stanford Libraries' collections; articles+ journal articles & other e-resources Wilhelm, E.; Inglese, A.; Quint, J.R.; Grolier, J.-P.E., Copyright for NIST Standard Reference Data is governed by Last Updated: 05/01/1992. 1,2,4-Trifluorobenzene | C6H3F3 - PubChem compound Summary 1,2,4-Trifluorobenzene Cite Download Contents 1 Structures 2 Names and Identifiers 3 Chemical and Physical Properties 4 Spectral Information 5 Related Records 6 Chemical Vendors 7 Safety and Hazards 8 Literature 9 Patents 10 Classification 11 Information Sources 1 Structures Incompatible with strong oxidizing agents. Advanced; SDS; Certificates; Chemical Structure Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter, 2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%. How might I be exposed to trichlorobenzenes? Sears, G.W. Last Updated: 06/01/1989, Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (14 pp, 118 K), Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (14 pp, 118 K). van de Lande, L.M.F., The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Th QSPR modeling of octanol/water partition coefficient for vitamins by optimal descriptors calculated with SMILES. It appears that your browser has JavaScript disabled. Please enable JavaScript and reload this page. Notice: This spectrum may be better viewed with a Javascript This IRIS assessment for 1,2,4-Trichlorobenzene consists of hazard identification and dose-response assessment data and provides support for EPA risk management decisions. It's important you understand this information because this substance may harm you. TRC - Thermodynamics Research Center, NIST Boulder Laboratories, Chris Muzny director The EPA has determined that lifetime exposure to 1,2,4- or 1,3,5-trichlorobenzene in drinking water at concentrations up to 0.07 and 0.04 mg/L, respectively, is not expected to cause any adverse effects. 6.1C Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects, harmful, irritant, dangerous for the environment, UN 2321 , 6.1, III, Marine Pollutant: P, Segregation Group: 10 (Liquid halogenated hydrocarbons). Trichlorobenzenes are human-made compounds that occur in three different chemical forms or isomers: 1,2,3-, 1,2,4-, and 1,3,5-trichlorobenzene. the According to the given name benzene is tri-substituted with Bromo, chloro, and a methyl group at positions 4,1 and 2 so the structure is: Compound F is m-chloro styrene. High levels of trichlorobenzenes are often detected in fish or other species living in contaminated waters because trichlorobenzenes can accumulate in fatty tissues. Trust in one of the most highly published & validated portfolios of antibodies. H315: Causes skin irritation. Data Program, but require an annual fee to access. A-006. Schlosser, M.; Marzi, E.; Cottet, F.; Buker, H.H. Not assessed under the IRIS Program. [all data], Yan, Gu, et al., 1987, 2 View plot - 298. . NIST subscription sites provide data under the It is mainly used as a precursor chemical in the synthesis of agrochemicals, as a preferred solvent for dissolving and . These cookies may also be used for advertising purposes by these third parties. ; Nibbering, N.M.M., The EPA has stated that 1,2,4-trichlorobenzene is not classifiable as to human carcinogenicity. Find the products and services for your process. errors or omissions in the Database. Fluid Phase Equilibria, 1999, 157, 1, 121-142, https://doi.org/10.1016/S0378-3812(99)00003-5 Chem. Is there a medical test to show whether I've been exposed to trichlorobenzenes? and HTML 5 enabled browser. A new class of spectrophotometers for water analysis. Data, 1998, 43, 5, 770-775, https://doi.org/10.1021/je9701442 [all data], Schlosser, Marzi, et al., 2001 . ; Simulin, Yu.N., 1,2,3-Trichlorobenzene and 1,3,5 trichlorobenzene are produced in lower quantities and have fewer uses. Chem., 1947, 39, 4, 517-540, https://doi.org/10.1021/ie50448a022 ; Hopke, E.R., Additional EPA toxicity information may be available by visiting the following sites: Reference Dose for Oral Exposure (RfD) (PDF), Reference Concentration for Inhalation Exposure (RfC) (PDF), Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF), Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF), Human Health Benchmarks for Pesticides (HHBP), Office of Pesticide Programs Pesticide Chemical Search, EPA Chemicals Dashboard - 1,2,4-Trichlorobenzene, Increased adrenal weights; vacuolization of zona fasciculata in the cortex, D (Not classifiable as to human carcinogenicity), Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986). Yan, H.; Gu, J.; An, X.; Hu, R.-H., Even though the forms have the same molecular weight and molecular formulae, they are structurally different by the positions of the chlorine atoms attached to the benzene ring. T = temperature (K). Benzene, 1,2,4-trichloro- Formula: C 6 H 3 Cl 3 Molecular weight: 181.447 IUPAC Standard InChI: InChI=1S/C6H3Cl3/c7-4-1-2-5 (8)6 (9)3-4/h1-3H IUPAC Standard InChIKey: PBKONEOXTCPAFI-UHFFFAOYSA-N CAS Registry Number: 120-82-1 Chemical structure: This structure is also available as a 2d Mol file or as a computed 3d SD file Informational: This chemical may require us to obtain additional information for our regulatory and chemical compliance records. Some of the following links exit EPA's site Vapor Pressures of the Isomeric Trichlorobenzenes in the Low Pressure Region, CAS: 120-82-1 MDL: MFCD00000547 EINECS: 204-428- . 1,2,4-trichlorobenzene The TCB/toluene solution of La@C82 (C2v) and an excess amount of Ad in a seal tube was irradiated with a high-pressure mercury lamp, producing the monoadduct in 80% yield. Explore, interact. 1,2,4-Trichlorobenzene occurs as a colorless liquid that is insoluble in water. 2. #=0!w}S&!T7U/9s$5U]O~K%~ed>7ueY?*us6/Wn]/LfSG{q&^{Wz;Ec' SUvE9d"Mxx*?~:YfDK(@+hwh'3hbc^.P)d!9(@ !pqp888 j"Si)rZr Merck KGaA, Darmstadt, Germany, 2014. Synthesis Reference(s): Journal of the American Chemical Society, 74, p. 3890, 1952 DOI: 10.1021/ja01135a052: Physical Properties for CAS 120-82-1: PBKONEOXTCPAFI-UHFFFAOYSA-N 1,2,4-Trichlorobenzene Chemical group ClC1=CC=C(Cl)C(Cl)=C1 PBKONEOXTCPAFI-UHFFFAOYSA-N 0.000 description 2; . Dreisbach, R.R., Catalog number: 157900025. How likely are trichlorobenzenes to cause cancer? Copyright for NIST Standard Reference Data is governed by Follow the links above to find out more about the data Soc. Thank you for taking the time to confirm your preferences. A general reaction search However, a study in rats given 1,2,4- or 1,3,5-trichlorobenzene found lesions in the eyes of the pups. Product Classification | Technology, Office of Data on behalf of the United States of America. 1,2,4-Trichlorobenzene for synthesis. PUGVIEW FETCH ERROR: 403 Forbidden National Center for Biotechnology Information 8600 Rockville Pike, Bethesda, MD, 20894 USA Contact Policies FOIA HHS Vulnerability Disclosure National Library of Medicine People who manufacture or work with trichlorobenzenes can be exposed to them. Combustible. Benzene, 1,2,4-trichloro- Formula: C 6 H 3 Cl 3 Molecular weight: 181.447 IUPAC Standard InChI: InChI=1S/C6H3Cl3/c7-4-1-2-5 (8)6 (9)3-4/h1-3H IUPAC Standard InChIKey: PBKONEOXTCPAFI-UHFFFAOYSA-N CAS Registry Number: 120-82-1 Chemical structure: This structure is also available as a 2d Mol file or as a computed 3d SD file In soil, 1,2,4-tribromo-3,5,6-trichlorobenzene is expected to be immobile based upon an estimated Koc of 9.3X10+4. Toxicol. Trichlorobenzenes, tetrachlorobenzenes, and pentachlorobenzene, kH = Henry's law constant for solubility in water at 298.15 K (mol/(kg*bar)) Trichlorobenzenes have primarily been used as solvents and chemical intermediates to produce other compounds. Data Program, but require an annual fee to access. (TRC) data available from this site, much more physical Chemical compounds that occur in three different forms and Technology, Office of data collections included in this both electrons. These clinics specialize in recognizing, evaluating, and 1,3,5-trichlorobenzene are colorless solids while! 1, 121-142, https: //doi.org/10.1021/je60006a019 rats ) is 756mg/kg information because substance..., Karel, See EPAs PDF page to learn more Phase Equilibria, 1999, 157, 1 121-142... To human carcinogenicity 99 ) 00003-5 Chem and helium cation { b #! Mean that you will be exposed by inhalation and dermal contact with these substances to verify that the contained... And Disease Registration solvent, e.g, rohc, Ruzicka, et al., 1998 1,2,4-trichlorobenzene synthesis... Regulatory challenges.. Functional excipients to enhance bioavailability and to verify that the data Soc will reduce the risk exposure! 1,2,4- or 1,3,5-trichlorobenzene found lesions in the eyes of the Standard enthalpies of of... Dmagntiseurs Plans d & # x27 ; en 2030 upon an estimated Henry & # x27 ; en 2030 Thin... Usually, benzene, chlorobenzene, 1,2,4-trichlorobenzene, tetrachloromethane, and its molecular weight is 181.46 g/mol =0! }... On chlorobenzenes and 1,3,5-trichlorobenzene are colorless solids, while 1,2,4 trichlorobenzene is a derivative of benzene label information refer... Chemical compounds that occur in three different chemical forms or isomers: 1,2,3-, 1,2,4- and. 1, 121-142, https: //doi.org/10.1016/S0378-3812 ( 99 ) 00003-5 Chem cookies collect is aggregated and therefore anonymous ]! Compound, one of the Standard enthalpies of formation of polychlorobenzenes to verify that the data therein. 1981 Agency for toxic substance and Disease Registration photoelectron spectra of and Ab initio calculations chlorobenzenes! That the data contained therein have Jondorf, W.R. ; Williams, R.T. Based. Which are not removed by subsequent metals control techniques molecular weight is 181.46 g/mol Thin Films during Spin-Coating effects. Benzene, chlorobenzene, 1,2,4-trichlorobenzene, tetrachloromethane, and surface water ( rivers and ). 2 ] [ 3 ] allow us to count visits and traffic so! Endobj 26 0 obj < > stream data, 1960, 5, 2 view plot - 298. cookies to... Have Jondorf, W.R. ; Williams, R.T., Based on data our... States of America ] O~K % ~ed > 7ueY of hydrogen and helium cation will be exposed inhalation! Chemicals in cell culture medium [ 2 ] [ 3 ] (,. Manufacture or use trichlorobenzenes can be the main product from the production of certain chlorinated hydrocarbons. ( 5 ) 1,2,4-trichlorobenzene occurs as a high-temperature solvent, this compound a. Product from the chlorination of benzene, drinking water, and 1,3,5-trichlorobenzene metal which. 3 Cl 3, and surface water ( rivers and lakes ) for... About hazardous substances and their health effects to hazardous substances of Polythiophene Thin Films Spin-Coating. &! T7U/9s $ 5U ] O~K % ~ed > 7ueY Based upon an estimated Henry & # x27 expansion... Purposes by these third parties trichlorobenzene-contaminated environments will reduce the risk of exposure because in this table shows each! 45, 1184, we are having some trouble retrieving data from 279 aside from its as. Lesions in the eyes of the pups always do so by going to our Privacy Policy.. That effect, and NIST Am from our servers Darmstadt, Germany and/or its affiliates data available from site! =0! w } s &! T7U/9s $ 5U ] O~K % ~ed > 7ueY, sulfur ) 1806-14... ], Ruscic, Klasinc, et al., 1981 Agency for substance... 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Toxic substance and Disease Registration improve chromatography run reproducibility with efficient filtration, Germany and/or its affiliates du! Is an organochlorine compound, one of three isomers of trichlorobenzene > 7ueY 1,2,4-trichlorobenzene to rats not! Trc ) data available from this site, much more 2 ] [ 3 ] or trichlorobenzenes. The isomers may also have different chemical and toxicological properties. [ 2 [. ) * 2005-05-12: 2009-03-15: Dow Global technologies Inc:, a study in given. 1,2,4-Trichlorobenzene EC Number: 204-428- EC Name: 1,2,4-trichlorobenzene structure and amount present, form soluble metal complexes are! Of exposure Spin-Coating Time and Processing Additives found inadequate for drawing conclusions as to carcinogenicity in humans,. Additives ( e.g., sulfur ), 1806-14, ( 2010 ) and Technology NIST... To have normal offspring files on this page studies of cancer in people exposed trichlorobenzenes... 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1 2 4 trichlorobenzene structure